Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 465.3 BDBM487728

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487728 (N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...) Show SMILES FC(F)(F)c1c(cnn1-c1ccnc2ccoc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1 Show InChI InChI=1S/C20H10F3N9O2/c21-20(22,23)17-13(10-29-31(17)15-1-3-25-14-2-6-34-16(14)15)19(33)30-12-7-11(8-24)18(26-9-12)32-27-4-5-28-32/h1-7,9-10H,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair