Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 484.8 BDBM487610

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487610 (N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...) Show SMILES FC(F)(F)c1c(cnn1-c1cncc2ccccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1 Show InChI InChI=1S/C21H12ClF3N8O/c22-16-7-13(9-27-19(16)33-28-5-6-29-33)31-20(34)15-10-30-32(18(15)21(23,24)25)17-11-26-8-12-3-1-2-4-14(12)17/h1-11H,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair