Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 464.9 BDBM50292641

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50292641 ((+/-)-1'-(4-chloro-3-(trifluoromethyl)benzyl)-3-ph...) Show SMILES FC(F)(F)c1cc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccc2)ccc1Cl Show InChI InChI=1S/C24H24ClF3N2O2/c25-20-7-6-16(14-19(20)24(26,27)28)15-30-12-9-18(10-13-30)23(17-4-2-1-3-5-17)11-8-21(31)29-22(23)32/h1-7,14,18H,8-13,15H2,(H,29,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...				Bioorg Med Chem Lett 18: 5819-23 (2009) Article DOI: 10.1016/j.bmcl.2008.07.115 BindingDB Entry DOI: 10.7270/Q2RV0NQB
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