Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 321.3 BDBM50416459

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50416459 (CHEMBL1209347) Show SMILES FC(F)(F)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H10F3N3S/c16-15(17,18)10-4-6-11(7-5-10)20-14-21-13(9-22-14)12-3-1-2-8-19-12/h1-9H,(H,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assay				Bioorg Med Chem Lett 20: 4741-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.140 BindingDB Entry DOI: 10.7270/Q2JS9QMP
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50416459 (CHEMBL1209347) Show SMILES FC(F)(F)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H10F3N3S/c16-15(17,18)10-4-6-11(7-5-10)20-14-21-13(9-22-14)12-3-1-2-8-19-12/h1-9H,(H,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline SpA Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor				Bioorg Med Chem Lett 20: 6103-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.041 BindingDB Entry DOI: 10.7270/Q2JM2BWB
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50416459 (CHEMBL1209347) Show SMILES FC(F)(F)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H10F3N3S/c16-15(17,18)10-4-6-11(7-5-10)20-14-21-13(9-22-14)12-3-1-2-8-19-12/h1-9H,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y1 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assay				Bioorg Med Chem Lett 20: 4741-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.140 BindingDB Entry DOI: 10.7270/Q2JS9QMP
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50416459 (CHEMBL1209347) Show SMILES FC(F)(F)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H10F3N3S/c16-15(17,18)10-4-6-11(7-5-10)20-14-21-13(9-22-14)12-3-1-2-8-19-12/h1-9H,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y2 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assay				Bioorg Med Chem Lett 20: 4741-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.140 BindingDB Entry DOI: 10.7270/Q2JS9QMP
					More data for this Ligand-Target Pair