Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Proline-rich AKT1 substrate 1
(Homo sapiens (Human)) | BDBM386028
(4-{4-[1-(4-trifluoro-phenyl)-2-(piperidin-yl)-ethy...)Show SMILES FC(F)(F)c1ccc(cc1)C(CN1CCCCC1)N1CCN(CC1)c1ncnc2NCC(=O)Nc12 Show InChI InChI=1S/C24H30F3N7O/c25-24(26,27)18-6-4-17(5-7-18)19(15-32-8-2-1-3-9-32)33-10-12-34(13-11-33)23-21-22(29-16-30-23)28-14-20(35)31-21/h4-7,16,19H,1-3,8-15H2,(H,31,35)(H,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin at Madison
| Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu... |
J Med Chem 51: 7243-52 (2008)
BindingDB Entry DOI: 10.7270/Q26M394B |
More data for this
Ligand-Target Pair | |
Ribosomal protein S6 kinase beta-1 [T412E]
(Homo sapiens (Human)) | BDBM386028
(4-{4-[1-(4-trifluoro-phenyl)-2-(piperidin-yl)-ethy...)Show SMILES FC(F)(F)c1ccc(cc1)C(CN1CCCCC1)N1CCN(CC1)c1ncnc2NCC(=O)Nc12 Show InChI InChI=1S/C24H30F3N7O/c25-24(26,27)18-6-4-17(5-7-18)19(15-32-8-2-1-3-9-32)33-10-12-34(13-11-33)23-21-22(29-16-30-23)28-14-20(35)31-21/h4-7,16,19H,1-3,8-15H2,(H,31,35)(H,28,29,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin at Madison
| Assay Description
P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... |
J Med Chem 51: 7243-52 (2008)
BindingDB Entry DOI: 10.7270/Q26M394B |
More data for this
Ligand-Target Pair | |