Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 504.4 BDBM50507040

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50507040 (CHEMBL4456694) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN=C1c1ccc(cc1)C1=NCCN1c1ccc(cn1)C(F)(F)F |c:14,t:24| Show InChI InChI=1S/C24H18F6N6/c25-23(26,27)17-5-7-19(33-13-17)35-11-9-31-21(35)15-1-2-16(4-3-15)22-32-10-12-36(22)20-8-6-18(14-34-20)24(28,29)30/h1-8,13-14H,9-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of Influenza A virus (A/Puerto Rico/8/34(H1N1)) PA endonuclease infected in MDCK cells assessed as reduction in virus titer treated with c...				Eur J Med Chem 161: 526-532 (2019) Article DOI: 10.1016/j.ejmech.2018.10.063 BindingDB Entry DOI: 10.7270/Q2ZW1Q61
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