Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM351717
(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)Show SMILES FC(F)(F)c1ccc2n(CC(=O)Nc3scc(Cl)c3-c3ncn(CCCN4CCOCC4)n3)c(=O)ccc2c1 Show InChI InChI=1S/C25H24ClF3N6O3S/c26-18-14-39-24(22(18)23-30-15-34(32-23)7-1-6-33-8-10-38-11-9-33)31-20(36)13-35-19-4-3-17(25(27,28)29)12-16(19)2-5-21(35)37/h2-5,12,14-15H,1,6-11,13H2,(H,31,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM351717
(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)Show SMILES FC(F)(F)c1ccc2n(CC(=O)Nc3scc(Cl)c3-c3ncn(CCCN4CCOCC4)n3)c(=O)ccc2c1 Show InChI InChI=1S/C25H24ClF3N6O3S/c26-18-14-39-24(22(18)23-30-15-34(32-23)7-1-6-33-8-10-38-11-9-33)31-20(36)13-35-19-4-3-17(25(27,28)29)12-16(19)2-5-21(35)37/h2-5,12,14-15H,1,6-11,13H2,(H,31,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM351717
(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)Show SMILES FC(F)(F)c1ccc2n(CC(=O)Nc3scc(Cl)c3-c3ncn(CCCN4CCOCC4)n3)c(=O)ccc2c1 Show InChI InChI=1S/C25H24ClF3N6O3S/c26-18-14-39-24(22(18)23-30-15-34(32-23)7-1-6-33-8-10-38-11-9-33)31-20(36)13-35-19-4-3-17(25(27,28)29)12-16(19)2-5-21(35)37/h2-5,12,14-15H,1,6-11,13H2,(H,31,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this
Ligand-Target Pair | |