Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 515.9 BDBM307863

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307863 (N-[5-chloro-4-(1-{[6-(trifluoromethyl)pyridin-2-yl...) Show SMILES FC(F)(F)c1cccc(CN2CCc3ccc(cc23)-c2cc(NC(=O)C3CCCNC3)ncc2Cl)n1 Show InChI InChI=1S/C26H25ClF3N5O/c27-21-14-32-24(34-25(36)18-3-2-9-31-13-18)12-20(21)17-7-6-16-8-10-35(22(16)11-17)15-19-4-1-5-23(33-19)26(28,29)30/h1,4-7,11-12,14,18,31H,2-3,8-10,13,15H2,(H,32,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
					More data for this Ligand-Target Pair