Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 284.2 BDBM50088799

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Sus scrofa)	BDBM50088799 (2-(2-Trifluoromethyl-benzoyl)-cyclohexane-1,3-dion...) Show SMILES FC(F)(F)c1ccccc1C(=O)C1C(=O)CCCC1=O Show InChI InChI=1S/C14H11F3O3/c15-14(16,17)9-5-2-1-4-8(9)13(20)12-10(18)6-3-7-11(12)19/h1-2,4-5,12H,3,6-7H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver				Bioorg Med Chem Lett 12: 2271-5 (2002) BindingDB Entry DOI: 10.7270/Q25H7GS3
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Sus scrofa)	BDBM50088799 (2-(2-Trifluoromethyl-benzoyl)-cyclohexane-1,3-dion...) Show SMILES FC(F)(F)c1ccccc1C(=O)C1C(=O)CCCC1=O Show InChI InChI=1S/C14H11F3O3/c15-14(16,17)9-5-2-1-4-8(9)13(20)12-10(18)6-3-7-11(12)19/h1-2,4-5,12H,3,6-7H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Tunghai Christian University Curated by ChEMBL					Assay Description Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate method				Bioorg Med Chem Lett 10: 843-5 (2000) BindingDB Entry DOI: 10.7270/Q2S75FK2
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Sus scrofa)	BDBM50088799 (2-(2-Trifluoromethyl-benzoyl)-cyclohexane-1,3-dion...) Show SMILES FC(F)(F)c1ccccc1C(=O)C1C(=O)CCCC1=O Show InChI InChI=1S/C14H11F3O3/c15-14(16,17)9-5-2-1-4-8(9)13(20)12-10(18)6-3-7-11(12)19/h1-2,4-5,12H,3,6-7H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)				Bioorg Med Chem Lett 12: 2271-5 (2002) BindingDB Entry DOI: 10.7270/Q25H7GS3
					More data for this Ligand-Target Pair