Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50304940
(CHEMBL591573 | N-phenethyl-4-(4-(2-(trifluoromethy...)Show SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C27H26F3N3O2/c28-27(29,30)24-9-5-4-8-23(24)26(35)33-18-16-32(17-19-33)22-12-10-21(11-13-22)25(34)31-15-14-20-6-2-1-3-7-20/h1-13H,14-19H2,(H,31,34) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50304940
(CHEMBL591573 | N-phenethyl-4-(4-(2-(trifluoromethy...)Show SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C27H26F3N3O2/c28-27(29,30)24-9-5-4-8-23(24)26(35)33-18-16-32(17-19-33)22-12-10-21(11-13-22)25(34)31-15-14-20-6-2-1-3-7-20/h1-13H,14-19H2,(H,31,34) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in human HEK-293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 ... |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |