Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50424789
(CHEMBL2315096)Show SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCCCC1CC1 Show InChI InChI=1S/C24H28F3N5O2/c25-24(26,27)19-7-2-1-6-18(19)23(34)32-15-13-31(14-16-32)21-11-10-20(29-30-21)22(33)28-12-4-3-5-17-8-9-17/h1-2,6-7,10-11,17H,3-5,8-9,12-16H2,(H,28,33) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af... |
J Med Chem 56: 568-83 (2013)
Article DOI: 10.1021/jm301661h BindingDB Entry DOI: 10.7270/Q25Q4XDG |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50424789
(CHEMBL2315096)Show SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCCCC1CC1 Show InChI InChI=1S/C24H28F3N5O2/c25-24(26,27)19-7-2-1-6-18(19)23(34)32-15-13-31(14-16-32)21-11-10-20(29-30-21)22(33)28-12-4-3-5-17-8-9-17/h1-2,6-7,10-11,17H,3-5,8-9,12-16H2,(H,28,33) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs |
J Med Chem 56: 568-83 (2013)
Article DOI: 10.1021/jm301661h BindingDB Entry DOI: 10.7270/Q25Q4XDG |
More data for this Ligand-Target Pair | |