Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 434.4 BDBM50305743

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50305743 (CHEMBL595386 | N-(2-cyclopropylethyl)-6-(4-(2-(tri...) Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1 Show InChI InChI=1S/C22H25F3N4O2/c23-22(24,25)17-3-1-2-4-19(17)31-16-10-13-29(14-11-16)20-8-7-18(27-28-20)21(30)26-12-9-15-5-6-15/h1-4,7-8,15-16H,5-6,9-14H2,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of SCD1 in rat liver microsomes				Bioorg Med Chem Lett 20: 499-502 (2010) Article DOI: 10.1016/j.bmcl.2009.11.111 BindingDB Entry DOI: 10.7270/Q26H4HH3
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