Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50312694
(1-(2-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl...)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc(s1)N1CCCC1=O Show InChI InChI=1S/C19H20F3N3O2S/c20-19(21,22)14-4-1-2-5-15(14)27-13-7-10-24(11-8-13)18-23-12-17(28-18)25-9-3-6-16(25)26/h1-2,4-5,12-13H,3,6-11H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 164 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in Wistar rat liver microsome assessed as [3H]stearoyl-CoA to [3H]oleoyl-CoA conversion pretreated 1 hr before [3H]stearoyl-CoA ad... |
Bioorg Med Chem Lett 20: 1593-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.083
BindingDB Entry DOI: 10.7270/Q2DJ5FR0 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50312694
(1-(2-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl...)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc(s1)N1CCCC1=O Show InChI InChI=1S/C19H20F3N3O2S/c20-19(21,22)14-4-1-2-5-15(14)27-13-7-10-24(11-8-13)18-23-12-17(28-18)25-9-3-6-16(25)26/h1-2,4-5,12-13H,3,6-11H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells assessed as [14C]stearic acid to [14C]oleic acid conversion pretreated 15 mins before [14C]stearic acid addit... |
Bioorg Med Chem Lett 20: 1593-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.083
BindingDB Entry DOI: 10.7270/Q2DJ5FR0 |
More data for this
Ligand-Target Pair | |