Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Branched-chain-amino-acid aminotransferase, cytosolic
(Rattus norvegicus) | BDBM50172933
(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)Show SMILES FC(F)(F)c1ccccc1S(=O)(=O)NNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C16H11ClF3N3O3S/c17-10-5-6-12-9(7-10)8-13(21-12)15(24)22-23-27(25,26)14-4-2-1-3-11(14)16(18,19)20/h1-8,21,23H,(H,22,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat BCATc |
Bioorg Med Chem Lett 16: 2337-40 (2006)
Article DOI: 10.1016/j.bmcl.2005.07.058 BindingDB Entry DOI: 10.7270/Q2F47NQZ |
More data for this Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, cytosolic
(Homo sapiens (Human)) | BDBM50172933
(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)Show SMILES FC(F)(F)c1ccccc1S(=O)(=O)NNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C16H11ClF3N3O3S/c17-10-5-6-12-9(7-10)8-13(21-12)15(24)22-23-27(25,26)14-4-2-1-3-11(14)16(18,19)20/h1-8,21,23H,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human BCATc |
Bioorg Med Chem Lett 16: 2337-40 (2006)
Article DOI: 10.1016/j.bmcl.2005.07.058 BindingDB Entry DOI: 10.7270/Q2F47NQZ |
More data for this Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50172933
(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)Show SMILES FC(F)(F)c1ccccc1S(=O)(=O)NNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C16H11ClF3N3O3S/c17-10-5-6-12-9(7-10)8-13(21-12)15(24)22-23-27(25,26)14-4-2-1-3-11(14)16(18,19)20/h1-8,21,23H,(H,22,24) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat BCATm |
Bioorg Med Chem Lett 16: 2337-40 (2006)
Article DOI: 10.1016/j.bmcl.2005.07.058 BindingDB Entry DOI: 10.7270/Q2F47NQZ |
More data for this Ligand-Target Pair | |