Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-secretase 1
(Homo sapiens (Human)) | BDBM314902
(US9611261, Example 425)Show SMILES FC(F)[C@]1(N=C(NC(=O)c2ccccc2)O[C@H]2C[C@@H]12)c1cc(Br)ccc1F |r,t:4| Show InChI InChI=1S/C19H14BrF3N2O2/c20-11-6-7-14(21)12(8-11)19(17(22)23)13-9-15(13)27-18(25-19)24-16(26)10-4-2-1-3-5-10/h1-8,13,15,17H,9H2,(H,24,25,26)/t13-,15+,19+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 613 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
US Patent
| Assay Description
The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic... |
US Patent US9611261 (2017)
BindingDB Entry DOI: 10.7270/Q21J9CW2 |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Homo sapiens (Human)) | BDBM314902
(US9611261, Example 425)Show SMILES FC(F)[C@]1(N=C(NC(=O)c2ccccc2)O[C@H]2C[C@@H]12)c1cc(Br)ccc1F |r,t:4| Show InChI InChI=1S/C19H14BrF3N2O2/c20-11-6-7-14(21)12(8-11)19(17(22)23)13-9-15(13)27-18(25-19)24-16(26)10-4-2-1-3-5-10/h1-8,13,15,17H,9H2,(H,24,25,26)/t13-,15+,19+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
US Patent
| Assay Description
Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ... |
US Patent US9611261 (2017)
BindingDB Entry DOI: 10.7270/Q21J9CW2 |
More data for this
Ligand-Target Pair | |