Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 484.3 BDBM372621

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372621 (N-[2-(4-Difluoromethoxy-3-fluoro-benzyl)-2H-[1,2,3...) Show SMILES FC(F)Oc1ccc(Cn2ncc(NC(=O)Cc3ccc(cc3)C3(CC3)C(F)(F)F)n2)cc1F Show InChI InChI=1S/C22H18F6N4O2/c23-16-9-14(3-6-17(16)34-20(24)25)12-32-29-11-18(31-32)30-19(33)10-13-1-4-15(5-2-13)21(7-8-21)22(26,27)28/h1-6,9,11,20H,7-8,10,12H2,(H,30,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair