Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 446.4 BDBM372623

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372623 (N-[2-(4-Difluoromethoxy-3-fluoro-benzyl)-2H-[1,2,3...) Show SMILES FC(F)Oc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCCC3)n2)cc1F Show InChI InChI=1S/C21H21F3N6O2/c22-16-9-15(3-5-17(16)32-21(23)24)13-30-26-12-18(28-30)27-20(31)10-14-4-6-19(25-11-14)29-7-1-2-8-29/h3-6,9,11-12,21H,1-2,7-8,10,13H2,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
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