Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50192540
((R)-4-(4-(4-(difluoromethoxy)phenyl)-2-oxo-2,3-dih...)Show SMILES FC(F)Oc1ccc(cc1)-c1cn(C2CCN(CC2)C(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(CC(F)(F)F)C2=O)c(=O)[nH]1 |t:25| Show InChI InChI=1S/C33H29F5N6O4/c34-30(35)48-23-12-10-20(11-13-23)25-18-43(32(47)39-25)22-14-16-42(17-15-22)31(46)41-28-29(45)44(19-33(36,37)38)26-9-5-4-8-24(26)27(40-28)21-6-2-1-3-7-21/h1-13,18,22,28,30H,14-17,19H2,(H,39,47)(H,41,46)/t28-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]CGRP from human recombinant CGRP receptor |
Bioorg Med Chem Lett 16: 5052-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.044
BindingDB Entry DOI: 10.7270/Q29S1QNX |
More data for this
Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50192540
((R)-4-(4-(4-(difluoromethoxy)phenyl)-2-oxo-2,3-dih...)Show SMILES FC(F)Oc1ccc(cc1)-c1cn(C2CCN(CC2)C(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(CC(F)(F)F)C2=O)c(=O)[nH]1 |t:25| Show InChI InChI=1S/C33H29F5N6O4/c34-30(35)48-23-12-10-20(11-13-23)25-18-43(32(47)39-25)22-14-16-42(17-15-22)31(46)41-28-29(45)44(19-33(36,37)38)26-9-5-4-8-24(26)27(40-28)21-6-2-1-3-7-21/h1-13,18,22,28,30H,14-17,19H2,(H,39,47)(H,41,46)/t28-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production |
Bioorg Med Chem Lett 16: 5052-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.044
BindingDB Entry DOI: 10.7270/Q29S1QNX |
More data for this
Ligand-Target Pair | |