Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 423.4 BDBM372539

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372539 (N-[2-(4-Cyano-benzyl)-2H-[1,2,3]triazol-4-yl]-2-[6...) Show SMILES FC1(F)CCN(C1)c1ccc(CC(=O)Nc2cnn(Cc3ccc(cc3)C#N)n2)cn1 Show InChI InChI=1S/C21H19F2N7O/c22-21(23)7-8-29(14-21)19-6-5-17(11-25-19)9-20(31)27-18-12-26-30(28-18)13-16-3-1-15(10-24)2-4-16/h1-6,11-12H,7-9,13-14H2,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
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