Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482511
(US10919852, Compound TABLE 1.210 | US11708326, Com...)Show SMILES FC1CCN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cc(cc(c3)C#N)C#N)c(CNC[C@H]3CCC(=O)N3)cc2Cl)CC1 |r| Show InChI InChI=1S/C44H44Cl2FN5O4/c45-38-21-31(25-50-26-33-8-11-43(53)51-33)41(55-27-30-19-28(23-48)18-29(20-30)24-49)22-42(38)56-39-10-9-35-34(4-1-5-36(35)39)37-6-2-7-40(44(37)46)54-17-3-14-52-15-12-32(47)13-16-52/h1-2,4-7,18-22,32-33,39,50H,3,8-17,25-27H2,(H,51,53)/t33-,39+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482511
(US10919852, Compound TABLE 1.210 | US11708326, Com...)Show SMILES FC1CCN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cc(cc(c3)C#N)C#N)c(CNC[C@H]3CCC(=O)N3)cc2Cl)CC1 |r| Show InChI InChI=1S/C44H44Cl2FN5O4/c45-38-21-31(25-50-26-33-8-11-43(53)51-33)41(55-27-30-19-28(23-48)18-29(20-30)24-49)22-42(38)56-39-10-9-35-34(4-1-5-36(35)39)37-6-2-7-40(44(37)46)54-17-3-14-52-15-12-32(47)13-16-52/h1-2,4-7,18-22,32-33,39,50H,3,8-17,25-27H2,(H,51,53)/t33-,39+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |