Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 448.4 BDBM50301655

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50301655 (CHEMBL567310 | trans-N-(5-(3-(fluoromethoxy)phenyl...) Show SMILES FCOc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:19.23,wD:16.16,(33.32,-25.03,;31.99,-25.81,;30.65,-25.04,;29.32,-25.82,;29.33,-27.37,;27.99,-28.14,;26.66,-27.37,;26.66,-25.83,;27.99,-25.06,;25.33,-25.06,;23.99,-25.83,;22.66,-25.06,;22.67,-23.52,;21.33,-22.75,;20,-23.52,;18.67,-22.75,;20,-25.06,;18.67,-25.84,;18.67,-27.38,;20,-28.14,;21.33,-27.38,;21.33,-25.84,;20.92,-29.39,;20.02,-30.65,;20.5,-32.11,;18.54,-30.18,;17.2,-30.95,;15.86,-30.18,;15.86,-28.64,;17.19,-27.87,;18.53,-28.63,;23.99,-22.75,;25.32,-23.51,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-18-3-1-2-16(10-18)17-11-27-23(28-12-17)29-21(30)15-4-7-24(8-5-15)20-6-9-26-13-19(20)22(31)33-24/h1-3,6,9-13,15H,4-5,7-8,14H2,(H,27,28,29,30)/t15-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 19: 5436-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q
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