Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin S
(Homo sapiens (Human)) | BDBM240641
(US9409882, 46)Show SMILES Fc1cc(Cl)cnc1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1-n1cccn1 |r| Show InChI InChI=1S/C27H24ClFN6O4S/c28-17-12-19(29)23(31-14-17)27(8-9-27)25(37)34-15-18(13-21(34)24(36)33-26(16-30)6-7-26)40(38,39)22-5-2-1-4-20(22)35-11-3-10-32-35/h1-5,10-12,14,18,21H,6-9,13,15H2,(H,33,36)/t18-,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 159 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh... |
US Patent US9409882 (2016)
BindingDB Entry DOI: 10.7270/Q2B56HNF |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM240641
(US9409882, 46)Show SMILES Fc1cc(Cl)cnc1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1-n1cccn1 |r| Show InChI InChI=1S/C27H24ClFN6O4S/c28-17-12-19(29)23(31-14-17)27(8-9-27)25(37)34-15-18(13-21(34)24(36)33-26(16-30)6-7-26)40(38,39)22-5-2-1-4-20(22)35-11-3-10-32-35/h1-5,10-12,14,18,21H,6-9,13,15H2,(H,33,36)/t18-,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh... |
US Patent US9409882 (2016)
BindingDB Entry DOI: 10.7270/Q2B56HNF |
More data for this
Ligand-Target Pair | |