Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin S
(Homo sapiens (Human)) | BDBM240611
(US9409882, 16)Show SMILES Fc1cc(Cl)cnc1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ncc(cc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C24H19Cl2F4N5O2S/c25-13-6-16(27)18(32-9-13)23(3-4-23)21(37)35-10-14(7-17(35)19(36)34-22(11-31)1-2-22)38-20-15(26)5-12(8-33-20)24(28,29)30/h5-6,8-9,14,17H,1-4,7,10H2,(H,34,36)/t14-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh... |
US Patent US9409882 (2016)
BindingDB Entry DOI: 10.7270/Q2B56HNF |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM240611
(US9409882, 16)Show SMILES Fc1cc(Cl)cnc1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ncc(cc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C24H19Cl2F4N5O2S/c25-13-6-16(27)18(32-9-13)23(3-4-23)21(37)35-10-14(7-17(35)19(36)34-22(11-31)1-2-22)38-20-15(26)5-12(8-33-20)24(28,29)30/h5-6,8-9,14,17H,1-4,7,10H2,(H,34,36)/t14-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh... |
US Patent US9409882 (2016)
BindingDB Entry DOI: 10.7270/Q2B56HNF |
More data for this
Ligand-Target Pair | |