Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 349.3 BDBM50565286

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50565286 (CHEMBL4778721) Show SMILES Fc1cc(F)cc(Oc2ccc3[nH]nc(\C=C\c4ccccn4)c3c2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TrkB (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112552 BindingDB Entry DOI: 10.7270/Q2W95DXR
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50565286 (CHEMBL4778721) Show SMILES Fc1cc(F)cc(Oc2ccc3[nH]nc(\C=C\c4ccccn4)c3c2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TrkC (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112552 BindingDB Entry DOI: 10.7270/Q2W95DXR
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50565286 (CHEMBL4778721) Show SMILES Fc1cc(F)cc(Oc2ccc3[nH]nc(\C=C\c4ccccn4)c3c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TrkA (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112552 BindingDB Entry DOI: 10.7270/Q2W95DXR
					More data for this Ligand-Target Pair