Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cholinesterase
(Equus caballus (Horse)) | BDBM50232664
(CHEMBL4076211)Show SMILES Fc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N2CCN(CCN3CCCC3)CC2)c2ccc(cc2)-c2ccccc2)cc1 |c:12| Show InChI InChI=1S/C39H43FN6O/c40-33-16-12-30(13-17-33)29-41-38(47)28-37-35-10-4-5-11-36(35)42-39(45-26-24-44(25-27-45)23-22-43-20-6-7-21-43)46(37)34-18-14-32(15-19-34)31-8-2-1-3-9-31/h1-5,8-19,37H,6-7,20-29H2,(H,41,47) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University
Curated by ChEMBL
| Assay Description
Inhibition of equine serum BCHE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m... |
Bioorg Med Chem Lett 27: 1179-1185 (2017)
Article DOI: 10.1016/j.bmcl.2017.01.068
BindingDB Entry DOI: 10.7270/Q2P271CH |
More data for this
Ligand-Target Pair | |
Voltage-dependent T-type calcium channel subunit alpha-1H
(Homo sapiens (Human)) | BDBM50232664
(CHEMBL4076211)Show SMILES Fc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N2CCN(CCN3CCCC3)CC2)c2ccc(cc2)-c2ccccc2)cc1 |c:12| Show InChI InChI=1S/C39H43FN6O/c40-33-16-12-30(13-17-33)29-41-38(47)28-37-35-10-4-5-11-36(35)42-39(45-26-24-44(25-27-45)23-22-43-20-6-7-21-43)46(37)34-18-14-32(15-19-34)31-8-2-1-3-9-31/h1-5,8-19,37H,6-7,20-29H2,(H,41,47) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University
Curated by ChEMBL
| Assay Description
Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ... |
Bioorg Med Chem 25: 4656-4664 (2017)
Article DOI: 10.1016/j.bmc.2017.07.010
BindingDB Entry DOI: 10.7270/Q2W95CNR |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Electrophorus electricus (Electric eel)) | BDBM50232664
(CHEMBL4076211)Show SMILES Fc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N2CCN(CCN3CCCC3)CC2)c2ccc(cc2)-c2ccccc2)cc1 |c:12| Show InChI InChI=1S/C39H43FN6O/c40-33-16-12-30(13-17-33)29-41-38(47)28-37-35-10-4-5-11-36(35)42-39(45-26-24-44(25-27-45)23-22-43-20-6-7-21-43)46(37)34-18-14-32(15-19-34)31-8-2-1-3-9-31/h1-5,8-19,37H,6-7,20-29H2,(H,41,47) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University
Curated by ChEMBL
| Assay Description
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi... |
Bioorg Med Chem Lett 27: 1179-1185 (2017)
Article DOI: 10.1016/j.bmcl.2017.01.068
BindingDB Entry DOI: 10.7270/Q2P271CH |
More data for this
Ligand-Target Pair | |