Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 497.9 BDBM517373

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM517373 (3-(2-chlorophenyl)-N-(1,1- dioxidotetrahydrothioph...) Show SMILES Fc1ccc(Cn2nc(-c3ccccc3Cl)c3ccc(cc23)C(=O)NC2CCS(=O)(=O)C2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZP497K
					More data for this Ligand-Target Pair