Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Anoctamin-1
(Homo sapiens (Human)) | BDBM509755
(4-[[2-(2,5-Difluorophenyl)acetyl]amino]-N-(4-fluor...)Show SMILES Fc1ccc(F)c(CC(=O)Nc2ccnc(c2)C(=O)NC23CC(F)(C2)CC3)c1 |(9.22,-.05,;7.89,-.82,;7.89,-2.36,;6.55,-3.13,;5.22,-2.36,;3.89,-3.13,;5.22,-.82,;3.89,-.05,;2.55,-.82,;2.55,-2.36,;1.22,-.05,;-.11,-.82,;-.11,-2.36,;-1.45,-3.13,;-2.78,-2.36,;-2.78,-.82,;-1.45,-.05,;-4.12,-.05,;-4.12,1.49,;-5.45,-.82,;-6.78,-.05,;-6.94,1.48,;-8.45,1.8,;-9.22,3.13,;-8.03,.28,;-9.22,.47,;-8.19,-.68,;6.55,-.05,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2KW5K8C |
More data for this
Ligand-Target Pair | |
Anoctamin-1
(Homo sapiens (Human)) | BDBM509755
(4-[[2-(2,5-Difluorophenyl)acetyl]amino]-N-(4-fluor...)Show SMILES Fc1ccc(F)c(CC(=O)Nc2ccnc(c2)C(=O)NC23CC(F)(C2)CC3)c1 |(9.22,-.05,;7.89,-.82,;7.89,-2.36,;6.55,-3.13,;5.22,-2.36,;3.89,-3.13,;5.22,-.82,;3.89,-.05,;2.55,-.82,;2.55,-2.36,;1.22,-.05,;-.11,-.82,;-.11,-2.36,;-1.45,-3.13,;-2.78,-2.36,;-2.78,-.82,;-1.45,-.05,;-4.12,-.05,;-4.12,1.49,;-5.45,-.82,;-6.78,-.05,;-6.94,1.48,;-8.45,1.8,;-9.22,3.13,;-8.03,.28,;-9.22,.47,;-8.19,-.68,;6.55,-.05,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M32ZXP |
More data for this
Ligand-Target Pair | |