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Target
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Marvin 2D Structure
The following exact ligands are found in BindingDB
Wt: 467.8
BDBM50601001
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
11
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
2.35E+3
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
BDBM50601001
(CHEMBL5207431)
Show SMILES
Fc1ccc(N2CCN(Cc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)CC2)c(Cl)c1
Show InChI
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00593
BindingDB Entry DOI:
10.7270/Q2FB571B
More data for this
Ligand-Target Pair