Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 372.4 BDBM50248398

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248398 (2-(4-fluorophenyl)-6-(piperidin-4-yl)-3-(pyrimidin...) Show SMILES Fc1ccc(cc1)-c1[nH]c2cc(ccc2c1-c1ccncn1)C1CCNCC1 Show InChI InChI=1S/C23H21FN4/c24-18-4-1-16(2-5-18)23-22(20-9-12-26-14-27-20)19-6-3-17(13-21(19)28-23)15-7-10-25-11-8-15/h1-6,9,12-15,25,28H,7-8,10-11H2	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
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