Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 326.3 BDBM417078

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM417078 (2-(4-Fluorophenyl)-5-(2-phenoxyethoxy)pyridazin-3(...) Show SMILES Fc1ccc(cc1)-n1ncc(OCCOc2ccccc2)cc1=O Show InChI InChI=1S/C18H15FN2O3/c19-14-6-8-15(9-7-14)21-18(22)12-17(13-20-21)24-11-10-23-16-4-2-1-3-5-16/h1-9,12-13H,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...				US Patent US10399948 (2019) BindingDB Entry DOI: 10.7270/Q2794726
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM417078 (2-(4-Fluorophenyl)-5-(2-phenoxyethoxy)pyridazin-3(...) Show SMILES Fc1ccc(cc1)-n1ncc(OCCOc2ccccc2)cc1=O Show InChI InChI=1S/C18H15FN2O3/c19-14-6-8-15(9-7-14)21-18(22)12-17(13-20-21)24-11-10-23-16-4-2-1-3-5-16/h1-9,12-13H,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of...				US Patent US10399948 (2019) BindingDB Entry DOI: 10.7270/Q2794726
					More data for this Ligand-Target Pair