Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 413.3 BDBM50508194

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50508194 (CHEMBL4450029) Show SMILES Fc1ccc(cc1)-n1ncc2c(cccc12)C(=O)NCc1ccccc1C(F)(F)F Show InChI InChI=1S/C22H15F4N3O/c23-15-8-10-16(11-9-15)29-20-7-3-5-17(18(20)13-28-29)21(30)27-12-14-4-1-2-6-19(14)22(24,25)26/h1-11,13H,12H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 441-448 (2019) Article DOI: 10.1016/j.bmcl.2018.12.024 BindingDB Entry DOI: 10.7270/Q2P55RT9
					More data for this Ligand-Target Pair