Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 439.8 BDBM430663

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM430663 ((3-(2-(4-chlorophenyl)thiazol-4-yl)-5,6-dihydro-[1...) Show SMILES Fc1ccc(cc1)C(=O)N1CCn2c(C1)nnc2-c1csc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H15ClFN5OS/c22-15-5-1-13(2-6-15)20-24-17(12-30-20)19-26-25-18-11-27(9-10-28(18)19)21(29)14-3-7-16(23)8-4-14/h1-8,12H,9-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ogeda SA US Patent					Assay Description The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...				US Patent US10544150 (2020) BindingDB Entry DOI: 10.7270/Q2XW4N7G
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