Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 398.4 BDBM430824

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM430824 ((4-fluorophenyl)(3-(2-(pyrrolidin-1-yl)thiazol-4-y...) Show SMILES Fc1ccc(cc1)C(=O)N1CCn2c(C1)nnc2-c1csc(n1)N1CCCC1 Show InChI InChI=1S/C19H19FN6OS/c20-14-5-3-13(4-6-14)18(27)25-9-10-26-16(11-25)22-23-17(26)15-12-28-19(21-15)24-7-1-2-8-24/h3-6,12H,1-2,7-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ogeda SA US Patent					Assay Description The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...				US Patent US10544150 (2020) BindingDB Entry DOI: 10.7270/Q2XW4N7G
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