Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 473.5 BDBM119414

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM119414 (US8669252, 69) Show SMILES Fc1ccc(cc1)C(NC(=O)[C@@H]1CC[C@H](C[C@H]1c1ccccc1)N1CCOCC1)c1ccncc1 |r| Show InChI InChI=1S/C29H32FN3O2/c30-24-8-6-22(7-9-24)28(23-12-14-31-15-13-23)32-29(34)26-11-10-25(33-16-18-35-19-17-33)20-27(26)21-4-2-1-3-5-21/h1-9,12-15,25-28H,10-11,16-20H2,(H,32,34)/t25-,26-,27+,28?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...				US Patent US8669252 (2014) BindingDB Entry DOI: 10.7270/Q2J9652X
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