Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50361758
(CHEMBL1938495)Show SMILES Fc1ccc(cc1)C(NC(=O)CCN1CCC(CC1)c1nc(no1)-c1ccccn1)c1ccncc1 Show InChI InChI=1S/C27H27FN6O2/c28-22-6-4-19(5-7-22)25(20-8-14-29-15-9-20)31-24(35)12-18-34-16-10-21(11-17-34)27-32-26(33-36-27)23-3-1-2-13-30-23/h1-9,13-15,21,25H,10-12,16-18H2,(H,31,35) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50361758
(CHEMBL1938495)Show SMILES Fc1ccc(cc1)C(NC(=O)CCN1CCC(CC1)c1nc(no1)-c1ccccn1)c1ccncc1 Show InChI InChI=1S/C27H27FN6O2/c28-22-6-4-19(5-7-22)25(20-8-14-29-15-9-20)31-24(35)12-18-34-16-10-21(11-17-34)27-32-26(33-36-27)23-3-1-2-13-30-23/h1-9,13-15,21,25H,10-12,16-18H2,(H,31,35) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasma |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this Ligand-Target Pair | |