Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM419831
(US10464919, Example 169)Show SMILES Fc1ccc(nc1)N1CCN(Cc2cc(F)c3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C22H23F2N5O/c23-15-3-4-19(26-12-15)29-8-6-28(7-9-29)13-14-10-17(24)20-18(11-14)27-22(30)16-2-1-5-25-21(16)20/h3-4,10-12,25H,1-2,5-9,13H2,(H,27,30) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.47 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd.
US Patent
| Assay Description
The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p... |
US Patent US10464919 (2019)
BindingDB Entry DOI: 10.7270/Q2736T8M |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human)) | BDBM419831
(US10464919, Example 169)Show SMILES Fc1ccc(nc1)N1CCN(Cc2cc(F)c3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C22H23F2N5O/c23-15-3-4-19(26-12-15)29-8-6-28(7-9-29)13-14-10-17(24)20-18(11-14)27-22(30)16-2-1-5-25-21(16)20/h3-4,10-12,25H,1-2,5-9,13H2,(H,27,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 32.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd.
US Patent
| Assay Description
The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ... |
US Patent US10464919 (2019)
BindingDB Entry DOI: 10.7270/Q2736T8M |
More data for this
Ligand-Target Pair | |
Activated CDC42 kinase 1
(Homo sapiens (Human)) | BDBM419831
(US10464919, Example 169)Show SMILES Fc1ccc(nc1)N1CCN(Cc2cc(F)c3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C22H23F2N5O/c23-15-3-4-19(26-12-15)29-8-6-28(7-9-29)13-14-10-17(24)20-18(11-14)27-22(30)16-2-1-5-25-21(16)20/h3-4,10-12,25H,1-2,5-9,13H2,(H,27,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 34.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd.
US Patent
| Assay Description
The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ... |
US Patent US10464919 (2019)
BindingDB Entry DOI: 10.7270/Q2736T8M |
More data for this
Ligand-Target Pair | |