Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 522.6 BDBM50084693

Wt: 522.6 BDBM50084704

Wt: 522.6 BDBM50084706

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50084693 (2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...) Show SMILES Fc1ccc2C(Cc3cccnc3)C(CCc2c1)NC(=O)CN1CC[C@@H](C1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H31FN4O3S/c29-22-9-10-25-21(16-22)8-11-27(26(25)15-20-5-4-13-30-17-20)31-28(34)19-33-14-12-23(18-33)32-37(35,36)24-6-2-1-3-7-24/h1-7,9-10,13,16-17,23,26-27,32H,8,11-12,14-15,18-19H2,(H,31,34)/t23-,26?,27?/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.				J Med Chem 43: 346-50 (2000) BindingDB Entry DOI: 10.7270/Q2XK8DS5
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50084704 (2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...) Show SMILES Fc1ccc2C(Cc3cccnc3)C(CCc2c1)NC(=O)CN1CCC(C1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H31FN4O3S/c29-22-9-10-25-21(16-22)8-11-27(26(25)15-20-5-4-13-30-17-20)31-28(34)19-33-14-12-23(18-33)32-37(35,36)24-6-2-1-3-7-24/h1-7,9-10,13,16-17,23,26-27,32H,8,11-12,14-15,18-19H2,(H,31,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.				J Med Chem 43: 346-50 (2000) BindingDB Entry DOI: 10.7270/Q2XK8DS5
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50084706 (2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...) Show SMILES Fc1ccc2C(Cc3cccnc3)C(CCc2c1)NC(=O)CN1CC[C@H](C1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H31FN4O3S/c29-22-9-10-25-21(16-22)8-11-27(26(25)15-20-5-4-13-30-17-20)31-28(34)19-33-14-12-23(18-33)32-37(35,36)24-6-2-1-3-7-24/h1-7,9-10,13,16-17,23,26-27,32H,8,11-12,14-15,18-19H2,(H,31,34)/t23-,26?,27?/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.				J Med Chem 43: 346-50 (2000) BindingDB Entry DOI: 10.7270/Q2XK8DS5
					More data for this Ligand-Target Pair