Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 368.3 BDBM50577665

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 7 (Homo sapiens (Human))	BDBM50577665 (CHEMBL4871202) Show SMILES Fc1ccc2c(n[nH]c2c1)-c1cccc(NS(=O)(=O)c2cccnc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length N-terminal GST tagged MEK7 expressed in Sf21 cells using JNK1 as substrate pre-incubated for 30 mins foll...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00376 BindingDB Entry DOI: 10.7270/Q20C50MC
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 4 (Homo sapiens (Human))	BDBM50577665 (CHEMBL4871202) Show SMILES Fc1ccc2c(n[nH]c2c1)-c1cccc(NS(=O)(=O)c2cccnc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00376 BindingDB Entry DOI: 10.7270/Q20C50MC
					More data for this Ligand-Target Pair