Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 386.5 BDBM50312020

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50312020 (CHEMBL1080100 | N-(4-(5,6-dihydro-4H-1,3-thiazin-2...) Show SMILES Fc1ccc2nc(NCCc3ccc(cc3)N=C3NCCCS3)sc2c1 |w:16.16| Show InChI InChI=1S/C19H19FN4S2/c20-14-4-7-16-17(12-14)26-19(24-16)22-10-8-13-2-5-15(6-3-13)23-18-21-9-1-11-25-18/h2-7,12H,1,8-11H2,(H,21,23)(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	318	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation counting				Bioorg Med Chem Lett 19: 6801-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z
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