Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50206957
(CHEMBL3902584 | US9518055, Example 35)Show InChI InChI=1S/C16H11F4N3/c17-12-3-4-13-22-14(15(9-1-2-9)23(13)8-12)10-5-11(7-21-6-10)16(18,19)20/h3-9H,1-2H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
US Patent
| Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ... |
US Patent US9518055 (2016)
BindingDB Entry DOI: 10.7270/Q23B625B |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50206957
(CHEMBL3902584 | US9518055, Example 35)Show InChI InChI=1S/C16H11F4N3/c17-12-3-4-13-22-14(15(9-1-2-9)23(13)8-12)10-5-11(7-21-6-10)16(18,19)20/h3-9H,1-2H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck USA
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B2-CLE9 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by s... |
Bioorg Med Chem Lett 27: 143-146 (2017)
Article DOI: 10.1016/j.bmcl.2016.12.003 BindingDB Entry DOI: 10.7270/Q20K2BK0 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50206957
(CHEMBL3902584 | US9518055, Example 35)Show InChI InChI=1S/C16H11F4N3/c17-12-3-4-13-22-14(15(9-1-2-9)23(13)8-12)10-5-11(7-21-6-10)16(18,19)20/h3-9H,1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck USA
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrat... |
Bioorg Med Chem Lett 27: 143-146 (2017)
Article DOI: 10.1016/j.bmcl.2016.12.003 BindingDB Entry DOI: 10.7270/Q20K2BK0 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50206957
(CHEMBL3902584 | US9518055, Example 35)Show InChI InChI=1S/C16H11F4N3/c17-12-3-4-13-22-14(15(9-1-2-9)23(13)8-12)10-5-11(7-21-6-10)16(18,19)20/h3-9H,1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
US Patent
| Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ... |
US Patent US9518055 (2016)
BindingDB Entry DOI: 10.7270/Q23B625B |
More data for this Ligand-Target Pair | |