Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50424795
(CHEMBL2315137)Show SMILES Fc1cccc(C(=O)N2CCN(CC2)c2ccc(nn2)C(=O)NCCC2CC2)c1C(F)(F)F Show InChI InChI=1S/C22H23F4N5O2/c23-16-3-1-2-15(19(16)22(24,25)26)21(33)31-12-10-30(11-13-31)18-7-6-17(28-29-18)20(32)27-9-8-14-4-5-14/h1-3,6-7,14H,4-5,8-13H2,(H,27,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af... |
J Med Chem 56: 568-83 (2013)
Article DOI: 10.1021/jm301661h
BindingDB Entry DOI: 10.7270/Q25Q4XDG |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50424795
(CHEMBL2315137)Show SMILES Fc1cccc(C(=O)N2CCN(CC2)c2ccc(nn2)C(=O)NCCC2CC2)c1C(F)(F)F Show InChI InChI=1S/C22H23F4N5O2/c23-16-3-1-2-15(19(16)22(24,25)26)21(33)31-12-10-30(11-13-31)18-7-6-17(28-29-18)20(32)27-9-8-14-4-5-14/h1-3,6-7,14H,4-5,8-13H2,(H,27,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs |
J Med Chem 56: 568-83 (2013)
Article DOI: 10.1021/jm301661h
BindingDB Entry DOI: 10.7270/Q25Q4XDG |
More data for this
Ligand-Target Pair | |