Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 435.9 BDBM307802

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307802 (5-chloro-4-[1-(3-fluorobenzyl)-1H-benzimidazol-6-y...) Show SMILES Fc1cccc(Cn2cnc3ccc(cc23)-c2cc(NC3CCCNC3)ncc2Cl)c1 Show InChI InChI=1S/C24H23ClFN5/c25-21-13-28-24(30-19-5-2-8-27-12-19)11-20(21)17-6-7-22-23(10-17)31(15-29-22)14-16-3-1-4-18(26)9-16/h1,3-4,6-7,9-11,13,15,19,27H,2,5,8,12,14H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
					More data for this Ligand-Target Pair