Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 418.4 BDBM50301646

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50301646 (CHEMBL584902 | trans-N-(5-(3-fluorophenyl)pyrimidi...) Show SMILES Fc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:17.21,wD:14.14,(29.51,-9.71,;28.18,-10.49,;28.18,-12.04,;26.85,-12.81,;25.52,-12.04,;25.52,-10.5,;26.84,-9.73,;24.18,-9.73,;22.85,-10.5,;21.52,-9.73,;21.52,-8.19,;20.19,-7.42,;18.86,-8.19,;17.52,-7.42,;18.86,-9.73,;17.53,-10.51,;17.53,-12.05,;18.86,-12.81,;20.19,-12.05,;20.19,-10.51,;19.78,-14.06,;18.87,-15.32,;19.36,-16.78,;17.39,-14.85,;16.05,-15.62,;14.72,-14.85,;14.72,-13.31,;16.05,-12.54,;17.38,-13.3,;22.85,-7.42,;24.18,-8.18,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-4-1-3-15(11-17)16-12-26-22(27-13-16)28-20(29)14-6-8-23(9-7-14)18-5-2-10-25-19(18)21(30)31-23/h1-5,10-14H,6-9H2,(H,26,27,28,29)/t14-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 19: 5436-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q
					More data for this Ligand-Target Pair