Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 354.3 BDBM50023761

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50023761 (CHEMBL3337665) Show SMILES Fc1cccc(c1)S(=O)(=O)N1CCc2cc(ccc12)-c1cccnc1 Show InChI InChI=1S/C19H15FN2O2S/c20-17-4-1-5-18(12-17)25(23,24)22-10-8-15-11-14(6-7-19(15)22)16-3-2-9-21-13-16/h1-7,9,11-13H,8,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate				J Med Chem 57: 7811-7 (2014) Article DOI: 10.1021/jm501004t BindingDB Entry DOI: 10.7270/Q2TQ634M
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50023761 (CHEMBL3337665) Show SMILES Fc1cccc(c1)S(=O)(=O)N1CCc2cc(ccc12)-c1cccnc1 Show InChI InChI=1S/C19H15FN2O2S/c20-17-4-1-5-18(12-17)25(23,24)22-10-8-15-11-14(6-7-19(15)22)16-3-2-9-21-13-16/h1-7,9,11-13H,8,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate				J Med Chem 57: 7811-7 (2014) Article DOI: 10.1021/jm501004t BindingDB Entry DOI: 10.7270/Q2TQ634M
					More data for this Ligand-Target Pair