Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human NPY Y4 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human NPY Y1 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human NPY Y2 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this Ligand-Target Pair | |