Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50511333
(CHEMBL4548077)Show SMILES Fc1ccccc1CCNC(=O)Cc1ccc(Oc2nc3ccccc3s2)cc1F Show InChI InChI=1S/C23H18F2N2O2S/c24-18-6-2-1-5-15(18)11-12-26-22(28)13-16-9-10-17(14-19(16)25)29-23-27-20-7-3-4-8-21(20)30-23/h1-10,14H,11-13H2,(H,26,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330
BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50511333
(CHEMBL4548077)Show SMILES Fc1ccccc1CCNC(=O)Cc1ccc(Oc2nc3ccccc3s2)cc1F Show InChI InChI=1S/C23H18F2N2O2S/c24-18-6-2-1-5-15(18)11-12-26-22(28)13-16-9-10-17(14-19(16)25)29-23-27-20-7-3-4-8-21(20)30-23/h1-10,14H,11-13H2,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330
BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this
Ligand-Target Pair | |