Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 280.2 BDBM50102120

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50102120 ((2R,4R)-4-amino-1-(2-hydroxybenzyl)pyrrolidine-2,4...) Show SMILES N[C@@]1(C[C@@H](N(Cc2ccccc2O)C1)C(O)=O)C(O)=O Show InChI InChI=1S/C13H16N2O5/c14-13(12(19)20)5-9(11(17)18)15(7-13)6-8-3-1-2-4-10(8)16/h1-4,9,16H,5-7,14H2,(H,17,18)(H,19,20)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 3				Bioorg Med Chem Lett 11: 1919-24 (2001) BindingDB Entry DOI: 10.7270/Q2SQ90XH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50102120 ((2R,4R)-4-amino-1-(2-hydroxybenzyl)pyrrolidine-2,4...) Show SMILES N[C@@]1(C[C@@H](N(Cc2ccccc2O)C1)C(O)=O)C(O)=O Show InChI InChI=1S/C13H16N2O5/c14-13(12(19)20)5-9(11(17)18)15(7-13)6-8-3-1-2-4-10(8)16/h1-4,9,16H,5-7,14H2,(H,17,18)(H,19,20)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2				Bioorg Med Chem Lett 11: 1919-24 (2001) BindingDB Entry DOI: 10.7270/Q2SQ90XH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50102120 ((2R,4R)-4-amino-1-(2-hydroxybenzyl)pyrrolidine-2,4...) Show SMILES N[C@@]1(C[C@@H](N(Cc2ccccc2O)C1)C(O)=O)C(O)=O Show InChI InChI=1S/C13H16N2O5/c14-13(12(19)20)5-9(11(17)18)15(7-13)6-8-3-1-2-4-10(8)16/h1-4,9,16H,5-7,14H2,(H,17,18)(H,19,20)/t9-,13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 6; Partial agonist				Bioorg Med Chem Lett 11: 1919-24 (2001) BindingDB Entry DOI: 10.7270/Q2SQ90XH
					More data for this Ligand-Target Pair