Found 7 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Parc Club Orsay Université
Curated by ChEMBL
| Assay Description Inhibitory activity of the compound against Metabotropic glutamate receptor 2 in the rat HEK 293 cells. |
J Med Chem 42: 1546-55 (1999)
Article DOI: 10.1021/jm980571q BindingDB Entry DOI: 10.7270/Q27H1HRD |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.56E+5 | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Effective concentration of compound against forskolin-stimulated cAMP formation in BHK cells expressing mGluR2 receptor |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for half-maximal stimulation of PI hydrolysis in BHK cells expressing mGluR1a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |