Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 306.3 BDBM50141755

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50141755 (3-Amino-3-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...) Show SMILES N[C@@H]([C@H](O)C(=O)N[C@@H](CO)c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C17H26N2O3/c18-15(13-9-5-2-6-10-13)16(21)17(22)19-14(11-20)12-7-3-1-4-8-12/h1,3-4,7-8,13-16,20-21H,2,5-6,9-11,18H2,(H,19,22)/t14-,15+,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human methionine aminopeptidase-2				Bioorg Med Chem Lett 14: 865-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50141755 (3-Amino-3-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...) Show SMILES N[C@@H]([C@H](O)C(=O)N[C@@H](CO)c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C17H26N2O3/c18-15(13-9-5-2-6-10-13)16(21)17(22)19-14(11-20)12-7-3-1-4-8-12/h1,3-4,7-8,13-16,20-21H,2,5-6,9-11,18H2,(H,19,22)/t14-,15+,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human methionine aminopeptidase-1				Bioorg Med Chem Lett 14: 865-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N
					More data for this Ligand-Target Pair