Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 319.3 BDBM24279

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24279 ((2S)-2-amino-N-[4-(cyclohexyloxy)phenyl]pentanedia...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OC2CCCCC2)cc1)C(N)=O |r| Show InChI InChI=1S/C17H25N3O3/c18-15(17(19)22)10-11-16(21)20-12-6-8-14(9-7-12)23-13-4-2-1-3-5-13/h6-9,13,15H,1-5,10-11,18H2,(H2,19,22)(H,20,21)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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